Glucagon-like peptide-1 (aka, GLP-1) is a pure hormone produced within the intestine and is vital to blood sugar regulation, how full we really feel, and slowing digestion. Boosting this pure hormone by means of dietary supplements helps help metabolic well being by means of balanced blood sugar, diminished irritation, much less insulin resistance, and improved intestine well being. And it could possibly additionally assist help girls with polycystic ovary syndrome (PCOS) by addressing a number of the commonest signs of the endocrine dysfunction.
The Hyperlink Between PCOS and GLP-1

“In girls with PCOS, insulin resistance and intestine well being imbalances might disrupt GLP-1 signaling,” says Jennifer Nicole Bianchini, MS, RD, IFNCP, RYT, a practical dietitian and mind-body wellness knowledgeable. “This may result in extra frequent starvation, blood sugar spikes, and issue managing weight.” Different signs, equivalent to cravings and vitality crashes, may also worsen with GLP-1 hormone imbalances. “That’s why something that lightly helps our physique’s pure GLP-1 manufacturing, like nourishing the intestine, selling wholesome digestion, and dietary supplements, may be a part of a wise, whole-body PCOS method,” she provides.
PCOS Signs
Along with blood sugar spikes, intestine well being imbalances, weight achieve, and insulin resistance, some widespread PCOS signs additionally embody hair thinning, pimples, oily pores and skin, oily hair, irregular or absent durations, reproductive challenges (hassle conceiving or subfertility), hair development on face, and darkish pores and skin across the neck, underarms, and alongside creases, says Dr. Nadia Musavvir, ND. These are the technical signs, however Dr. Musavvir says it’s not only a hormonal or reproductive challenge. “It’s metabolic and tends to be [caused by] underlying irritation, blood sugar dysregulation, together with hormonal imbalances.”
How GLP-1 Can Assist With PCOS Signs
In response to Dr. Sabrina Solt, NMD, naturopathic medical physician and founding father of Stem Cell Remedy Professionals, many ladies with PCOS have some extent of insulin resistance, which not solely worsens hormone imbalances but additionally blunts the physique’s pure GLP-1 response. She explains that this may grow to be a vicious cycle of impaired GLP-1 perform that then contributes to weight achieve and blood sugar instability, which then additional disrupts the hormonal panorama.
Balancing GLP-1 manufacturing by means of a pure GLP-1 booster just like the HUM Diet Flatter Me Fiber GLP-1 Booster may help deal with some PCOS signs and help girls with the widespread endocrine dysfunction by means of the advantages of fiber. “There are specific sorts of fibers which were proven to naturally stimulate GLP-1 launch within the intestine, which might promote emotions of fullness and assist help wholesome digestion,” Bianchini explains. “For girls with PCOS, fiber is vital to help intestine well being, bowel regularity, digestion, and blood sugar steadiness.”
Strengthening the intestine setting may also not directly help pure GLP-1 exercise, resulting in a extra regulated urge for food and diminished blood sugar spikes after meals. Nonetheless, taking a GLP-1 supporting complement isn’t the one key to focusing on GLP-1 for PCOS. Bianchini additionally recommends way of life adjustments like getting a very good number of greens, fiber, protein, and wholesome fat in your plate, plus stress administration to “encourage your physique’s personal built-in urge for food and blood sugar regulation system.”
FAQs
How Does GLP-1 Have an effect on Estrogen?
GLP-1 doesn’t instantly influence estrogen ranges, nor can it enhance estrogen. Nonetheless, estrogen naturally helps GLP-1 launch and the 2 work collectively (particularly by way of weight administration) to handle metabolic well being. Estrogen may also enhance GLP-1 advantages.
Does GLP-1 Assist Steadiness Hormones?
GLP-1 can naturally steadiness out hormones by means of its results on metabolic well being and weight administration. Ladies with PCOS can profit from the results of GLP-1 (and even taking dietary supplements that increase GLP-1 manufacturing, just like the HUM Diet Flatter Me Fiber GLP-1 Booster and Better of Berberine) since it could possibly assist deal with insulin resistance, steadiness blood sugar ranges, and goal irritation, all of that are widespread hormone disruptors.
The Takeaway
GLP-1 may be useful in managing PCOS signs, particularly round weight administration, insulin resistance, irritation, and blood sugar. By taking a GLP-1 boosting complement such because the HUM Diet Flatter Me Fiber GLP-1 Booster, which makes use of fiber to naturally stimulate GLP-1, or Better of Berberine for insulin resistance, you possibly can goal metabolic signs of PCOS.